Mark cullen gardner biography for kids
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Columbine High School massacre
1999 mass shooting in Columbine, Colorado, US
"Columbine massacre" and "Columbine shooting" redirect here. For the 1927 labor violence, see Columbine Mine massacre.
| Columbine High School massacre | |
|---|---|
Harris (left) and Klebold (right) in the cafeteria at 11:57 a.m. | |
| Location | Columbine, Colorado, U.S. |
| Date | April 20, 1999; 25 years ago (1999-04-20) 11:19 a.m. – 12:08 p.m. (MDT) |
| Target | Students and staff at Columbine High School, first responders |
Attack type | School shooting, mass shooting, mass murder, murder–suicide, arson, attempted bombing, shootout |
| Weapons | |
| Deaths | 15 (including both perpetrators) |
| Injured | 24 (21 by gunfire) |
| Perpetrators | Eric Harris and Dylan Klebold |
| Motive | Undetermined |
| Convicted | Mark Manes and Philip Duran (weapons suppliers) |
| Convictions | Manes and Duran: Supplying a handgun to a minor, possession of an illegally sawed-off shotgun |
| Sentence | Manes: 6 years in prison Duran: 4+1⁄2 years in prison[1][2] |
| Litigation | Multiple lawsuits against the perpetrators' families and suppliers of the weapons[a] |
A school shooting and attempted bombing occurred on April 20, 1999, at Columbine High School in Co
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Abstract
We present a case of a 25-year-old female with diagnosed familial adenomatous polyposis and elevated carcinoembryonic antigen with negative family history. The suspicion of Gardner's syndrome was raised because extirpation of an osteoma of the left temporo-occipital region was made 10 years ago. Restorative procto-colectomy and ileal pouch anal anastomosis was made but histology delineated adenocarcinoma of the rectum (Dukes C stage). We conclude that cranial osteomas often precede gastrointestinal manifestations of familial adenomatous polyposis or Gardner's syndrome and such patients should be evaluated with genetic testing followed by colonoscopy if results are positive to prevent the development of colorectal carcinoma. If the diagnosis is positive all family members should be evaluated for familial adenomatous polyposis.
Keywords: Gardner’s syndrome, Familial adenomatous polyposis, Restorative proctocolectomy, Ileal pouch anal anastomosis, Cranial osteoma
INTRODUCTION
Familial adenomatous polyposis (FAP)[1] and Gardner’s syndrome (GS)[2] were originally described as two different syndromes. The incidence of FAP is between 1 in 8300 and 1 in 14 025 live births affecting both genders equally, with a uniform worldwide distribution[3]. The incidence of GS is lo